abstract：OBJECTIVE:To examine glucose-regulated protein 78 (GRP78; a major molecular chaperone at the endoplasmic reticulum, strongly expressed in several tumours) expression in urothelial carcinoma (UC) of the upper urinary tract (UUT) and to evaluate the diagnostic and progressive importance of GRP78 expression in UC-UUT. PA...

journal_title：BJU international

authors： Uematsu K,Ogata S,Nakanishi K,Hiroi S,Tominaga S,Aida S,Kawai T

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To explore whether the number of unfavourable pretreatment risk factors predicts cause-specific mortality in men treated with prostate brachytherapy. PATIENTS AND METHODS:Between April 1995 and March 2006, 739 patients were treated who had at least one of the following adverse risk factors: pretreatment pros...

journal_title：BJU international

authors： Taira AV,Merrick GS,Galbreath RW,Butler WM,Lief JH,Wallner KE

更新日期：2010-09-01 00:00:00

abstract：:• Mid-urethral synthetic slings (MUSS) have grown in acceptance and popularity to gain a foremost position in stress urinary incontinence (SUI) surgery. • There are numerous studies that provide a large amount of Level 1 and 2 evidence that support the concept of a sling placed at the level of the mid-urethra. • Long-...

journal_title：BJU international

authors： Fong ED,Nitti VW

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of sustained-release (SR) bupropion to placebo in treating hypoactive sexual desire disorder (HSDD) in ovulating women. PATIENTS AND METHODS:After a 1-week, placebo lead-in phase, 232 treatment-seeking women with regular menstrual cycles were randomly assigned to bupropion SR 150 mg/d...

journal_title：BJU international

authors： Safarinejad MR,Hosseini SY,Asgari MA,Dadkhah F,Taghva A

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:To evaluate whether Raman molecular imaging (RMI, which combines digital imaging and analytical spectroscopy to evaluate the biochemical composition of interrogated material) can be used to identify biochemical differences in patients with Gleason 7 prostate cancer who progress to metastatic disease and die f...

journal_title：BJU international

authors： Tollefson M,Magera J,Sebo T,Cohen J,Drauch A,Maier J,Frank I

更新日期：2010-08-01 00:00:00

abstract：STUDY TYPE:Therapy (case series) Level of Evidence 4. OBJECTIVE:To report our analysis of the oncological outcome, side-effects and complications after (125)I-brachytherapy, based on 10 years of experience, as low dose-rate (LDR) prostate brachytherapy is an accepted, effective and safe therapy for localized prostate ...

journal_title：BJU international

authors： Prada PJ,Juan G,González-Suárez H,Fernández J,Jimenez I,Amón J,Cepeda M

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To evaluate extended lymph node dissection (LND) as a nodal staging tool in the treatment of invasive carcinoma of the urinary bladder and to suggest a reasonable proximal limit of the dissection. PATIENTS AND METHODS:In all, 170 patients underwent radical cystectomy with extended LND up to the level of the ...

journal_title：BJU international

authors： Jensen JB,Ulhøi BP,Jensen KM

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between perineural invasion (PNI) on prostate biopsy and radical prostatectomy (RP) outcomes in a contemporary RP series, as there is conflicting evidence on the prognostic significance of PNI in prostate needle biopsy specimens. PATIENTS AND METHODS:From 2002 to 2007, 1256 men ...

journal_title：BJU international

authors： Loeb S,Epstein JI,Humphreys EB,Walsh PC

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To present the outcomes of cT3N0M0 prostate cancer after radical prostatectomy (RP) and determine the prognostic factors in biochemical progression-free survival (BPFS), clinical progression-free survival (CPFS), cancer-specific survival (CSS) and overall survival (OS) after long-term follow-up of 10 years. ...

journal_title：BJU international

authors： Hsu CY,Wildhagen MF,Van Poppel H,Bangma CH

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To purify human muscle-derived cells (hMDCs) that could be used for managing urinary incontinence, erectile dysfunction and for bladder reconstitution. MATERIALS AND METHODS:hMDCs isolated by a modified preplate technique (MPT) from skeletal muscles of limbs were purified by CD34 antibody and magnetic Dynabe...

journal_title：BJU international

authors： Lu SH,Yang AH,Chen KK,Chiang HS,Chang LS

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To assess the overall and disease-specific survival rates of patients undergoing robot-assisted radical cystectomy (RARC) compared with historical open cystectomy. PATIENTS AND METHODS:Survival, pathological and demographic data were collected on all patients undergoing RARC for bladder cancer from both Tula...

journal_title：BJU international

authors： Martin AD,Nunez RN,Pacelli A,Woods ME,Davis R,Thomas R,Andrews PE,Castle EP

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To describe the clinical and magnetic resonance imaging (MRI) characteristics of vaginal and paraurethral leiomyomas. PATIENTS AND METHODS:All patients with pathologically confirmed paraurethral and vaginal wall leiomyomas from January 2006 to August 2007 were reviewed. Patients with no preoperative MRI of t...

journal_title：BJU international

authors： Hubert KC,Remer EM,Rackley RR,Goldman HB

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To develop and validate an Arabic version of the International Prostate Symptom Score (IPSS). PATIENTS, SUBJECTS AND METHODS:An Arabic version of the IPSS (IPSS-Arb) was developed through a series of translations and modifications which involved the authors, urology and non-urology medical and nursing staff....

journal_title：BJU international

authors： Hammad FT,Kaya MA

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To determine if the adjunctive use of power Doppler imaging (PDI) could provide prognostic utility in the treatment of prostate cancer, as an accurate prediction of the clinical behaviour of prostate cancer is important to determine appropriate treatment. PATIENTS AND METHODS:Most centres rely on a digital r...

journal_title：BJU international

authors： Eisenberg ML,Cowan JE,Carroll PR,Shinohara K

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To measure the time and subjective quality of individual steps of robot-assisted radical prostatectomy (RARP), as RARP performed by trainees has recently become the most common technique of RP in the USA, and although outcomes from expert surgeons are reported, limited data are available to document training ...

journal_title：BJU international

authors： Davis JW,Kamat A,Munsell M,Pettaway C,Pisters L,Matin S

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES:To report the medium-term results at our institution of repairing long bulbar urethral strictures with buccal mucosal grafts. PATIENTS AND METHODS:Between January 2003 and June 2007, a buccal mucosa graft repair was used in 34 patients with recurrent bulbar strictures >2 cm. The follow-up included uroflowme...

journal_title：BJU international

authors： Fransis K,Vander Eeckt K,Van Poppel H,Joniau S

更新日期：2010-04-01 00:00:00

abstract：:There has been a recent increase in mumps orchitis among pubertal and postpubertal males. These outbreaks can be attributed to a reduction in the uptake of measles-mumps-rubella (MMR) vaccine during the early to mid-1990 s in children who have now matured. The mumps virus is commonly associated with extra-salivary com...

journal_title：BJU international

authors： Davis NF,McGuire BB,Mahon JA,Smyth AE,O'Malley KJ,Fitzpatrick JM

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of zoledronic acid (ZA) in osteoporotic patients with prostate cancer receiving either luteinizing hormone-releasing hormone agonists (LHRHA, which accelerate bone loss) or bicalutamide (which preserves bone mineral density, BMD) as androgen-deprivation therapy is the mainstay of trea...

journal_title：BJU international

authors： Wadhwa VK,Weston R,Parr NJ

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of renal function on the stone-free rate (SFR) of proximal ureteric stones (PUS) after extracorporeal shock wave lithotripsy (ESWL), as urinary obstruction caused by PUS can impair renal function, and elevated serum creatinine levels are associated with decreased ureteric stone passa...

journal_title：BJU international

authors： Hung SF,Chung SD,Wang SM,Yu HJ,Huang HS

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To describe our current procedure of robot-assisted laparoscopic radical prostatectomy (RALP), and to assess the effect of the learning curve on perioperative data, early oncological outcomes and functional results, as RALP has increasingly become a treatment option for men with localized prostate cancer. PA...

journal_title：BJU international

authors： Ploussard G,Xylinas E,Salomon L,Vordos D,Hoznek A,Abbou CC,De La Taille A

更新日期：2010-04-01 00:00:00

abstract：:OBJECTIVE To describe the rationale and design of the Bladder Cancer Prognosis Programme (BCPP), and to demonstrate the capability of this design. METHODS There is a need to understand the determinants of bladder cancer to help reduce recurrence, progression, morbidity, mortality and related costs. We previously showe...

journal_title：BJU international

authors： Zeegers MP,Bryan RT,Langford C,Billingham L,Murray P,Deshmukh NS,Hussain S,James N,Wallace DM,Cheng KK

更新日期：2010-03-01 00:00:00

abstract：:Detailed molecular insights into bladder cancer biology might allow more detailed prognostication and optimization of treatment with the objective of improving patient outcome and quality of life. However, in bladder cancer research the search for biomarkers has been called into question and has even obtained notoriet...

journal_title：BJU international

authors： Bryan RT,Zeegers MP,James ND,Wallace DM,Cheng KK

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:To present our initial operative experience in which single-port-light endoscopic robot-assisted reconstructive and extirpative urological surgery was performed by one surgeon, using a pig model. MATERIALS AND METHODS:This pilot study was conducted in male farm pigs to determine the feasibility and safety o...

journal_title：BJU international

authors： Crouzet S,Haber GP,White WM,Kamoi K,Goel RK,Kaouk JH

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To investigate the effectiveness of a combined treatment of 3-30-methylene-bis[4-hydroxycoumarin] (dicoumarol) with doxorubicin for the treatment of urothelial cancer, as doxorubicin is a common chemotherapeutic agent but its therapeutic efficacy is limited. MATERIALS AND METHODS:The synergistic effect of di...

journal_title：BJU international

authors： Matsui Y,Watanabe J,Ding S,Nishizawa K,Kajita Y,Ichioka K,Saito R,Kobayashi T,Ogawa O,Nishiyama H

更新日期：2010-02-01 00:00:00

abstract：STUDY TYPE:Therapy (case series). LEVEL OF EVIDENCE:4. OBJECTIVE:To present our institution's experience of selective embolization of renal angiomyolipomas with alcohol and the long-term follow up data. PATIENTS AND METHODS:This retrospective study included 34 patients treated between October 1997 and October 2007 (...

journal_title：BJU international

authors： Chick CM,Tan BS,Cheng C,Taneja M,Lo R,Tan YH,Lin SE,Tay KH

更新日期：2010-02-01 00:00:00

abstract：:While patient age and gender are important factors in the clinical decision-making for treating urothelial carcinoma of the bladder (UCB), there are no evidence-based recommendations to guide healthcare professionals. We review previous reports on the influence of age and gender on the incidence, biology, mortality an...

journal_title：BJU international

authors： Shariat SF,Sfakianos JP,Droller MJ,Karakiewicz PI,Meryn S,Bochner BH

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To present the renal functional outcomes for patients treated with open partial nephrectomy (OPN) or radiofrequency ablation (RFA) for tumours in a solitary kidney, as renal masses in a solitary kidney present a challenging treatment dilemma. PATIENTS AND METHODS:A retrospective review of institutional datab...

journal_title：BJU international

authors： Raman JD,Raj GV,Lucas SM,Williams SK,Lauer EM,Ahrar K,Matin SF,Leveillee RJ,Cadeddu JA

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:To describe a 25-year experience of using the Whitaker test in a single tertiary centre for assessing upper urinary tract dilatation, and to evaluate the role of perfusion pressure-flow studies in contemporary urological surgery for equivocal upper tract obstruction. PATIENTS AND METHODS:In all, 143 patients...

journal_title：BJU international

authors： Lupton EW,George NJ

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To examine a large, single-surgeon series of patients with prostate cancer who underwent retropubic radical prostatectomy (RRP) for men with postoperative bladder neck contractures (BNCs). PATIENTS AND METHODS:From 1983 to 2007, 4132 men underwent RRP for prostate cancer by one surgeon. All patients had BN r...

journal_title：BJU international

authors： Erickson BA,Meeks JJ,Roehl KA,Gonzalez CM,Catalona WJ

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To evaluate changes in bone mass and fracture risk in patients with prostate cancer on androgen-deprivation therapy (ADT) and with a basal T-score of >-2.0, who were treated with an oral bisphosphonate, as such patients treated with ADT are at increased risk of bone loss and bone fracture. PATIENTS AND METHO...

journal_title：BJU international

authors： Planas J,Trilla E,Raventós C,Cecchini L,Orsola A,Salvador C,Placer J,Encabo G,Morote J

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To assess the outcomes for patients with Gleason score 8-10 prostate cancer treated with brachytherapy, external beam radiotherapy (EBRT) and hormonal therapy (HT). PATIENTS AND METHODS:In all, 181 patients with Gleason scores 8-10 prostate cancer were treated from 1994 to 2006 with a (103)Pd implant (prescr...

journal_title：BJU international

authors： Stock RG,Cesaretti JA,Hall SJ,Stone NN

更新日期：2009-12-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is among the most resistant tumours to chemotherapy, radiotherapy and hormonal therapy. Cytokine therapy is effective in a small subset of patients, but it is associated with substantial toxicity and rarely benefits patients with extensive tumour burdens or adverse prognostic factors. Since ...

journal_title：BJU international

authors： Mulders P

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Pelvi-ureteric junction (PUJ) obstruction is characterized by a functionally significant impairment of urinary transport caused by intrinsic or extrinsic obstruction in the area where the ureter joins the renal pelvis. The majority of cases are congenital in origin; however, acquired conditions at the level ...

journal_title：BJU international

authors： Uberoi J,Disick GI,Munver R

更新日期：2009-12-01 00:00:00

abstract：UNLABELLED:To determine whether dendritic cells (DC) transduced with the prostate-specific antigen (PSA) gene can induce PSA-specific cytotoxic lymphocytes (CTL) against prostate cancer cells, and whether bacillus Calmette-Guérin (BCG) cell-wall skeleton (CWS) can enhance the maturation of DC-PSA and the killing activi...

journal_title：BJU international

authors： Fujii R,Iwahashi M,Kikkawa K,Inagaki T,Kohjimoto Y,Ojima T,Mori T,Kuramoto T,Nishizawa S,Azuma I,Yamaue H,Shinka T,Hara I

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To correlate the results of intraoperative cavernous nerve stimulation (CaNS) at radical prostatectomy (RP), with preoperative erectile function (EF) and to determine the significance of the results of stimulation after RP in predicting the recovery of EF. PATIENTS AND METHODS:The study included 183 potent m...

journal_title：BJU international

authors： Rabbani F,Patel M,Cozzi P,Mulhall JP,Scardino PT

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To report a contemporary series of patients with xanthogranulomatous pyelonephritis (XGP, an inflammatory condition of the kidney that has traditionally been treated with open nephrectomy, ON), managed with either ON or laparoscopic nephrectomy (LN), as early reports suggest that the benefits of LN do not ext...

journal_title：BJU international

authors： Guzzo TJ,Bivalacqua TJ,Pierorazio PM,Varkarakis J,Schaeffer EM,Allaf ME

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term results and predictive risk factors for efficacy after the tension-free vaginal tape (TVT) procedure for treating female stress urinary incontinence (SUI). PATIENTS AND METHODS:Inall, 306 women (mean age 50.7 years, sd 8.7) who had a TVT procedure for SUI were selected and followed ...

journal_title：BJU international

authors： Song PH,Kim YD,Kim HT,Lim HS,Hyun CH,Seo JH,Yoo ES,Park CH,Jung HC,Gomelsky A

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between symptom severity and patient perceptions in patients with overactive bladder (OAB), as estimated by OAB Symptom Score (OABSS) and patient-reported outcome measures, respectively. PATIENTS AND METHODS:Post-hoc analyses were conducted on the existing data from patients with O...

journal_title：BJU international

authors： Homma Y,Gotoh M

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:To investigate the feasibility, tolerability, safety and efficacy of using a new surgical technique for the repair of anterior urethral strictures to preserve vascular supply to the urethra and its entire muscular and neurogenic support. PATIENTS AND METHODS:In all, 24 patients (mean age 46 years) underwent ...

journal_title：BJU international

authors： Kulkarni S,Barbagli G,Sansalone S,Lazzeri M

更新日期：2009-10-01 00:00:00

abstract：:Urothelial cell carcinomas (UCC), including bladder cancer and upper urinary tract cancer, are the second most common malignancy of the urogenital tract after prostate cancer. It is a critical issue to differentiate accurately those patients whose tumour will recur and/or progress after initial treatment from those wi...

journal_title：BJU international

authors： Phé V,Cussenot O,Rouprêt M

更新日期：2009-10-01 00:00:00